Marinol (Dronabinol)

Definition - What does Marinol (Dronabinol) mean?

Marinol (generic name: dronabinol) is a man-made pharmaceutical form of cannabis that has been approved by the United States Food and Drug Administration (FDA). It is widely used to treat nausea and vomiting in cancer patients undergoing chemotherapy.

Marinol is also often used to treat AIDS patients suffering from weight loss due to lack of appetite. The active ingredient in Marinol is a synthetic form of tetrahydrocannabinol (THC). THC occurs naturally in the cannabis plant. Marinol is taken orally in the form of a capsule. It has been available by prescription since 1985.

Hydrolife explains Marinol (Dronabinol)

Marinol works like the naturally occurring cannabinoids found in cannabis; it binds to the body's nervous system receptors. Despite its similarities to the natural cannabinoids of the cannabis plant, Marinol is entirely synthetic and created in a laboratory setting.

Unfortunately, it is not as effective as the natural cannabinoids found in cannabis plant material. Marinol is not very soluble and the human liver quickly metabolizes the substance so that only 10 to 20 per cent effectively reaches the body’s circulation.

With cannabis, a patient can ingest the cannabinoids and THC in a variety of ways such as smoking, vaping, or through edibles. Cannabis contains 66 identifiable chemical compounds. It is believed that those compounds work together to create beneficial health effects. However, unlike natural cannabis, Marinol only contains the synthetic cannabinoid THC.

Researchers believe that Marinol often does not work as well as cannabis because, in order for a patient to reap the many health benefits of THC, a variety of cannabinoids and other compounds must be present to work together naturally. Marinol lacks the many cannabinoids, terpenes, trichomes, and other compounds of natural cannabis.

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